APPETON VITAMIN C 500MG

Vitamin C reduces the severity and duration of symptoms associated with colds and flu. It plays important roles in the formation of collagen, tissue repair and wound healing. In addition it aids in the absorption of iron and also acts as an antioxidant vitamin, scavenging free radicals.

Vitamin C Supplementation And Common Cold Symptoms: Factors Affecting The Magnitude Of The Benefit

Placebo-controlled trails have shown that vitamin C supplementation decreases the duration and severity of common cold infections. However, the magnitude of the benefit had substantially varied, hampering conclusions about the clinical significance of the vitamin. 23 studies with regular vitamin C supplementation were analyzed to find out factors that may explain some part of the variation in the results. It was found that an average, vitamin C produces greater benefit for children than for adults. The dose may also affect the magnitude of the benefit, there being on average greater benefit from > 2g/day compared to 1g/day of the vitamin. In five studies with adults administered 2g/day the median decrease was four times higher, 26%. The trials analyzed in this work used regular vitamin C supplementation, but it is conceivable that therapeutic supplementation starting early at the onset of the cold episode could produce comparable benefits. Since few trials have examined the effects of the therapeutic supplementation and their results have been variable, further therapeutic trials are required to examine the role of vitamin C in the treatment of cold. Asthma , Inhaled Oxidants, and Dietary Antioxidants The possible influence of dietary antioxidants, especially vitamin C, on the in creasing prevalen ce of asthma is explored. Vitamin C intake in the general population appears to correlate with asthma, suggesting that a diet low in vitamin C is a risk fa ctor for asthma. Epidemiologi cal studies show asso ciations among oxidant exposure, respiratory infe ctions, and asthma in children of smokers. Symptoms of ongoing asthma in adults appear to be in creased by exposure to environmental oxidants and de creased by vitamin C supplementation. There is eviden ce that oxidants produ ced endogenously by overa ctive inflammatory cells contribute to ongoing asthma. Vitamin C is the major antioxidant substan ce present in the airway surfa ce liquid of the lung, where it could be important in prote cting against both endogenous and exogenous oxidants. Nitrogen oxides are exemplary of oxidants that could arise from both endogenous and environmental sour ces, whi ch are prote cted against by vitamin C, and that may be important in causation and propagation of asthma.  Vitamin C as an Antioxidant: Evaluation of Its Role in Disease Prevention Vitamin C in humans must be ingested for survival. Vitamin C is an electron donor, and this property accounts for all its known functions. As an electron donor, vitamin C is a potent water-soluble antioxidant in humans. Antioxidant effects of vitamin C have been demonstrated in many experiments in vitro. Human diseases such as atherosclerosis and cancer might occur in part from oxidant damage to tissues. Oxidation of lipids, proteins and DNA results in specific oxidation products that can be measured in the laboratory. While these biomarkers of oxidation have been measured in humans, such assays have not yet been validated or standardized, and the relationship of oxidant markers to human disease conditions is not clear. Epidemiological studies show that diets high in fruits and vegetables are associated with lower risk of cardiovascular disease, stroke and cancer, and with increased longevity. Whether these protective effects are directly attributable to vitamin C is not known. Intervention studies with vitamin C have shown no change in markers of oxidation or clinical benefit. Dose concentration studies of vitamin C in healthy people showed a sigmoidal relationship between oral dose and plasma and tissue vitamin C concentrations. Hence, optimal dosing is critical to intervention studies using vitamin C. Ideally, future studies of antioxidant actions of vitamin C should target selected patient groups. These groups should be known to have increased oxidative damage as assessed by a reliable biomarker or should have high morbidity and mortality due to diseases thought to be caused or exacerbated by oxidant damage. Relation of Serum Ascorbic Acid to Helicobacter pylori Serology in US Adults: The Third National Health and Nutrition Examination Survey  Purpose: To examine the relation between serum ascorbic acid and Helicobacter pylori serology from a probability sample of US adults. Results: A total of 2,189 adults (32%) had a positive serology for H. pylori, and, of these, 1,175 (54%) were positive for the CagA antigen. Among whites, a 0.50 mg/dL increase in serum ascorbic acid level was associated with decreased seroprevalence of H. pylori (Odds Ratio (OR) = 0.89, 95% confidence interval (CI) CI 0.82–0.96, p < 0.01). In analyses that controlled for seroprevalence of H. pylori, a 0.50 mg/dL increase in serum ascorbic acid level among whites was independently associated with a decreased seroprevalence of the pathogenic cagA-positive strain of H. pylori (OR = 0.31, 95% CI 0.12–0.79, p < 0.05). Serum ascorbic acid levels were not significantly associated with H. pylori serology among non-whites (all p > 0.05). Conclusions: Higher serum levels of ascorbic acid were associated with a decreased seroprevalence of H. pylori and of the pathogenic cagA-positive strain of H. pylori among whites. If these associations are related causally and are not the result of residual confounding by factors such as socioeconomic status, ascorbic acid may affect the risk of H. pylori infection and in turn, the risk for peptic ulcer disease and gastric cancer among white Americans. Influence Of Environmental Tobacco Smoke On Vitamin C Status in Children  Background: It is known that vitamin C status is compromised in smokers. The vitamin C status of nonsmokers who are exposed to environmental toba cco smoke (ETS) is now being elucidated. Objective: We assessed vitamin C status in children who were either exposed or not exposed to ETS, and we sought to asso ciate changes in vitamin C status with the amount of ETS exposure. Results: Plasma as corbate con centrations were lower, by 3.2 µmol/L on average, in ETS-exposed children than in unexposed children who consumed equivalent amounts of vitamin C; this was a highly signifi cant differen ce (P = 0.002). This reduction in plasma as corbate o ccurred even with very low exposure to ETS. Conclusions ETS can redu ce con centrations of as corbate, an important blood antioxidant, even when the amount of smoke exposure is minimal. Children exposed to ETS should be en couraged to consume in creased amounts of foods ri ch in vitamin C or should be given the equivalent amount of this vitamin as a supplement.  Note : Now I tried this product because I dropped the body's immunity. So, I tried to increase my endurance by trying this vitamin. Easily found in any pharmacy near you. Alhamdulillah itself to prove an increase in.